Artemether is a medication used for the treatment of malaria. The injectable form is specifically used for severe malaria rather than quinine. It may not be as effective as artesunate. It is given by injection in a muscle. It is also available by mouth in combination with lumefantrine, known as artemether/lumefantrine.
Artemether causes relatively few side effects. An irregular heartbeat may rarely occur. While there is evidence that use during pregnancy may be harmful in animals models, there is no evidence of concerns in humans. The World Health Organization therefore recommends it use during pregnancy. It is in the artemisinin class of medication.
Artemether has been studied since at least 1981 and been in medical use since 1987. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is between 0.38 and 16.47 USD per vial. The combination form cost between 100 and 200 USD for a course of treatment in the United States.[