Sodium perchlorate, anhydrous is a chaotropic agent used in standard DNA extraction and hybridization reactions in molecular biology. Often preferred over phenol extraction's because the sodium perchlorate/chloroform extraction technique is less time consuming and poses fewer hazards to the technician. Sodium perchlorate prevents binding of phenolic compounds to RNA during extraction. Eluent component used for analysis of biological samples by liquid chromatography. This compound is anhydrous.